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  • Keratoconus Screening for Children With Down Syndrome: An Irish Program Found Many Cases

    Keratoconus is a condition in which the clear front window of the eye, the cornea, thins and bulges into a cone shape, blurring vision. It is known to be more common in people with Down syndrome, and it can be harder to notice in children who may not report blurry vision. A study published in November 2026 in the journal Cornea describes a dedicated screening program for children with Down syndrome in Ireland.

    How the program worked

    From March 2019 to April 2026, children with Down syndrome were referred to a keratoconus screening program in Dublin. The program used corneal tomography, a scan that maps the shape and thickness of the cornea. The researchers reviewed records for all 45 children screened. The average age was 13.5 years.

    What they found

    • Useful scans were obtained in 40 of 45 children (88.9%), showing that outpatient screening was workable for most.
    • At the first visit, 15 children (33.3%) had keratoconus or suspected keratoconus.
    • During follow-up, 2 children with initially normal scans developed suspicious findings, and 3 children progressed to confirmed keratoconus.
    • In total, 18 of 45 children (40%) screened positive over time.

    The authors concluded that repeated tomography-based checks should be part of routine eye care for children with Down syndrome, because a reassuring first scan did not rule out later changes.

    What families can do

    • Ask your child’s eye doctor whether corneal tomography screening is appropriate, and how often to repeat it.
    • Watch for frequent eye rubbing, squinting, head tilting, or glasses that never seem to help; mention these at visits.
    • Treat eye allergies and discourage eye rubbing, which is linked to keratoconus.
    • If keratoconus is found, a cornea specialist can explain the options for monitoring, vision correction with glasses or specialty lenses, and other treatments suited to your child.

    This was a single-center study with a small group, so the exact percentages may not apply everywhere. But the message is clear: for children with Down syndrome, regular corneal checks matter. For more plain-language reading on eye health, see lalasikcost.com.

    Source: Diagnostic Yield and Longitudinal Performance of a Dedicated Keratoconus Screening Program for Children With Down Syndrome (Cornea (PubMed), 11/03/2026). This article is an educational summary written by Khanna Vision Institute and is not a substitute for medical advice.

  • Which Eye Drops Work Best for Sjögren’s Dry Eye? A Large Review Compares Them

    Sjögren’s syndrome is an autoimmune disease in which the immune system attacks the glands that make tears and saliva. Severe dry eye is one of its hallmark symptoms. A network meta-analysis published in Frontiers in Immunology compared topical treatments for the eye in Sjögren’s and found that some drops, such as autologous serum and cyclosporine, may help different symptoms.

    What a network meta-analysis does

    Most studies compare one treatment to a placebo. A network meta-analysis pools many studies and uses statistics to compare several treatments with each other, even if they were never tested head to head. It gives a broader picture of how options stack up.

    The options studied

    • Cyclosporine drops, which calm inflammation and can help the eye make more natural tears over time
    • Autologous serum drops, made from a patient’s own blood, which contain growth factors and nutrients similar to natural tears
    • Other anti-inflammatory and lubricating drops

    The takeaway is that there is no single best drop for everyone. Different treatments may do better for symptoms, surface staining, or tear production, so care should be personalized.

    Why this matters for keratoconus patients

    People with keratoconus often wear specialty contact lenses such as scleral or rigid lenses. Dry eye from any cause, including autoimmune disease, can make those lenses uncomfortable and affect corneal health. Controlling the eye surface is part of good keratoconus care and helps patients get the most out of their lenses.

    Signs you should be evaluated

    • Constant gritty or burning eyes
    • Dry mouth along with dry eyes
    • Difficulty tolerating contact lenses
    • Light sensitivity

    Help from Khanna Vision Institute

    Dr. Khanna’s team evaluates dry eye and keratoconus together, so treatment fits your whole eye. Patients come to us from Los Angeles, Beverly Hills, Westlake Village, and Thousand Oaks.

    More eye-health articles at Better Vision At Any Age.

    Source: Comparative efficacy and safety of topical therapies for ocular involvement in Sjögren's syndrome: a systematic review and network meta-analysis (Front Immunol (PubMed), 09/10/2026). This article is an educational summary written by Khanna Vision Institute and is not a substitute for medical advice.

  • Keratoconus and Eye Rubbing: Pressing, Knuckles and Habits Patients May Not Notice

    Keratoconus is a condition in which the cornea, the clear front window of the eye, becomes thinner and bulges into a cone shape, distorting vision. Eye rubbing has long been discussed as a risk factor. A study from the University of Osaka, with a collaborator from the Rothschild Foundation in Paris, suggests that asking “Do you rub your eyes?” may miss much of the story.

    What the researchers did

    Koh and colleagues studied 304 Japanese outpatients diagnosed with keratoconus in at least one eye. Each completed a structured questionnaire about current and past habits, followed by a face-to-face interview with a physician. Questions covered reasons, duration, frequency, technique, and where on the eye the pressure was applied.

    What they found

    • 91.4% of patients reported some form of mechanical eye stimulation.
    • These habits were usually long-standing; 75.9% had them for more than 10 years.
    • Itching was the most common trigger (75.9%), but many behaviors had nothing to do with itching.
    • Fingertips (56.1%) and knuckles (48.6%) were commonly used.
    • The inner corner of the eye was the most common site (70.1%).
    • About one-third reported pressure habits such as pressing or massaging the eyes when tired.

    The authors proposed “mechanical ocular stimulation” as a broader framework than eye rubbing, and said asking about current and past behaviors in detail may improve assessment and counseling.

    Questions worth asking yourself

    • Do you press on your eyes when you are tired, or rub the inner corners with a knuckle?
    • Do itchy, allergic eyes make you rub without thinking?

    What helps

    In my practice I ask about these habits in detail, not just with a yes-or-no question. Treating itch and allergy, using cool compresses instead of rubbing, and building awareness can reduce the urge. Tell your eye doctor about any habit, even one that seems minor, and keep your scheduled corneal mapping visits so changes are caught early.

    For more plain-language eye-health reading, see malibulasik.com.

    Source: Beyond Eye Rubbing: Mechanical Ocular Stimulation Is Highly Prevalent in Keratoconus (Eye & Contact Lens (PubMed), epub 09/29/2026). This article is an educational summary written by Khanna Vision Institute and is not a substitute for medical advice.

  • Paediatric Keratoconus: What a 2026 European Consensus Says About Catching It Early

    Keratoconus in children and teens often moves faster than the same diagnosis in adults, and many kids are already in a moderate or advanced stage by the time someone names it. In 2026, the European Reference Network for Rare Eye Diseases (ERN-EYE) published a clinical consensus statement on how to spot, confirm, and follow paediatric keratoconus—work built by a multidisciplinary panel across eight European countries using a structured Delphi process.

    Why timing matters in kids

    The cornea is still changing through adolescence. Progressive near-sightedness, a shifting astigmatism axis, or against-the-rule / oblique myopic astigmatism that worsens over months should raise suspicion. Best-corrected acuity can still look normal early on, so waiting for a bad eye chart alone is not enough. Family history of keratoconus and persistent ocular allergy—especially atopic disease with rubbing—are extra reasons to look carefully.

    How the consensus frames screening and diagnosis

    • Corneal tomography (including Scheimpflug imaging of the front and back of the cornea) belongs in the work-up when recent-onset corneal astigmatism appears, and—drawing on the Global Consensus on Keratoconus and Ectatic Diseases—when children ages 6–18 have more than 2 diopters of astigmatism on subjective refraction.
    • Retinoscopy remains valuable: a scissoring reflex or oil-droplet sign can flag suspicion even in a child who cannot sit for a full map, and it may be the only practical screen in a non-cooperative patient.
    • Diagnosis rests on clinical exam plus imaging; posterior elevation and focal thinning support ectasia on tomography or OCT.
    • For families with known keratoconus, earlier exams around ages 8–13 make sense, with yearly follow-up once astigmatism appears—even if that astigmatism still looks “regular” on a simple refraction.

    Follow-up rhythm the experts agreed on

    After a paediatric diagnosis, the statement emphasizes close monitoring: roughly every three to four months at first, then about yearly until age 18, with more frequent visits if measurements show progression. Collaboration between paediatricians and eye doctors helps catch kids who present first with allergy, rubbing, or “just another glasses change.” Patient and family education—especially stopping eye rubbing—is part of care, not an afterthought.

    James, a teen whose astigmatism jumped twice in one school year, is the kind of story that should trigger mapping, not another routine glasses update alone. Munson’s sign (a V-shaped lower-lid notch on downgaze) is a late, nonspecific clue; useful imaging should already have answered the question long before that appears.

    What families can do now

    • Bring old prescriptions so your doctor can see how fast the cylinder and axis are moving.
    • Mention allergy, rubbing, and any relative with keratoconus at the visit.
    • Ask whether topography or tomography is appropriate—not only a Snellen chart and phoropter.
    • Keep follow-up appointments; paediatric ectasia is a moving target through the teen years.

    For more regional eye-health reading, browse 1800realdoctor.com.

    Source: Paediatric Keratoconus: An ERN-EYE Clinical Consensus Statement on Diagnosis, Treatment and Follow-Up Care (Ophthalmology and Therapy / PubMed PMID 42538519; ERN-EYE / ESCRS coverage). This article is an educational summary written by Khanna Vision Institute and is not a substitute for medical advice.